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Organic compounds that contain an aromatic ring with one or more hydrogen atoms replaced by a halogen atom; also known as haloarene or halogenoarene. Halogen atoms include bromine, chlorine, fluorine, iodine.
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Iodo-PEG3-N3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups. PROTACs employ the intracellular ubiquitin-proteasome system to specifically degrade target proteins.
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MyoMed 205 is an inhibitor that targets the activity of MuRF1. It prevents early diaphragmatic systolic dysfunction and atrophy caused by unilateral diaphragmatic nerve denervation. This compound reduces ubiquitination and subsequent proteasomal degradation of muscle proteins by inhibiting MuRF1 activity. It also increases the levels of a protein that phosphorylates Akt (ser473), a crucial signaling molecule for muscle growth and maintenance. MyoMed 205 can be used for studying and treating diaphragmatic dysfunction and atrophy (DIDD).
Targets the activity of MuRF1.
Prevents early diaphragmatic systolic dysfunction and atrophy.
Reduces ubiquitination and proteasomal degradation of muscle proteins.
Increases levels of protein that phosphorylates Akt (ser473).
Useful for studying and treating diaphragmatic dysfunction and atrophy (DIDD).
For research use only.
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Benzene, (ethoxymethyl)- (CAS 539-30-0) is an endogenous metabolite supplied as a high-purity analytical standard for research and analytical workflows. It is commonly used as a reference standard in chromatographic and mass spectrometric analyses and as a reagent in chemical research.
High purity for analytical applications (~99%).
Liquid, colorless to light yellow, density ~0.949 g/cm3.
Molecular weight 136.19 g/mol; formula C9H12O.
Supplied with certificate of analysis and datasheet for quality assurance.
Recommended storage conditions provided to preserve stability.
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5-Iodo-A-85380 dihydrochloride is a high-affinity, small-molecule ligand and agonist for neuronal nicotinic acetylcholine receptors, with strong selectivity for the α4β2 subtype. It is supplied as the dihydrochloride salt for research use only and has a reported binding Kd of ≈12-14 pM.
High affinity for α4β2 nicotinic acetylcholine receptors (Kd ≈12-14 pM).
Selective agonist activity at α4β2 and α6β2 receptor subtypes.
Supplied as the dihydrochloride salt for improved stability and handling.
High purity suitable for research use (≈99.0%).
Available in small-scale pack sizes for laboratory studies.
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5-Iodo-cytidine is a purine nucleoside analogue with broad antitumor activity targeting indolent lymphoid malignancies. Its anticancer mechanisms involve inhibition of DNA synthesis and induction of apoptosis.
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4-(Ethoxymethyl)phenol is a small-molecule phenolic compound used in laboratory research as an antioxidant and analytical reference standard. It is a low-molecular-weight aromatic ether suitable for biochemical assays, analytical testing, and redox studies.
Phenolic antioxidant properties useful for redox and cytogenotoxicity studies.
High purity suitable for analytical and research applications.
Small, stable aromatic ether with molecular formula C9H12O2 and molecular weight 152.19 g/mol.
Supplied in small-mass quantities for precise dosing in experiments.
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Iodo-PEG3-N3 is a laboratory chemical primarily used in the manufacture of substances. This product is intended for research use only and should be handled by suitably qualified experienced scientists in appropriately equipped and authorized facilities. It has not been fully validated for medical applications.
Appearance: light yellow to yellow liquid
Molecular formula: C8H16IN3O3
Molecular weight: 329.14
NMR spectrum consistent with structure
Stable under recommended storage conditions
Recommended storage temperature: 4°C, protect from light
In solvent: -80°C for 6 months; -20°C for 1 month (protect from light)
Shipping at room temperature if less than 2 weeks
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DEC-205/CD205 Protein an endocytic receptor transports captured antigens to a specialized processing compartment placing it at the forefront of antigen presentation This role is crucial for immune surveillance and initiating immune responses DEC-205/CD205 s involvement also downregulates B-lymphocyte proliferation showcasing its regulatory impact on immune cell dynamics and responses DEC-205/CD205 Protein Human (HEK293 His) is the recombinant human-derived DEC-205/CD205 protein expressed by HEK293 with C-His labeled tag
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